引用本文:朱宏亮,万立华.小鼠脑组织细胞色素C氧化酶活性、线粒体细胞色素含量与年龄关系[J].重庆医科大学学报,2012,37(12):1041~1044
小鼠脑组织细胞色素C氧化酶活性、线粒体细胞色素含量与年龄关系
Relationship among CCO activity,contents of Cyt C in mitochondria of brain tissues and mice age
DOI:
中文关键词:  细胞色素C氧化酶  细胞色素C  线粒体  年龄推断
英文关键词:cytochrome C oxidase  cytochrome C  mitochondria  age estimation
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作者单位
朱宏亮,万立华 重庆医科大学基础医学院法医学教研室重庆 400016 
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中文摘要:
      目的:研究小鼠脑细胞色素C氧化酶(Cytochrome C oxidase,CCO)活性、线粒体细胞色素C(Cytochrome C,Cyt C)含量与年龄的关系,为法医学年龄推断提供新的思路。方法:利用紫外分光光度法检测了1、3、6、9、12月龄昆明小鼠的脑组织CCO活性及线粒体Cyt C含量。结果:小鼠脑组织CCO活性、线粒体Cyt C含量,随着年龄增大而逐渐降低。结论:脑组织CCO活性及线粒体Cyt C含量有望用于年龄推断。
英文摘要:
      Objective:To provide new ideas for forensic age estimation by studying relationship among cytochrome C oxidase(CCO)activity,contents of cytochrome C(Cyt C) in mitochondria of brain tissues and mice age. Methods:CCO activity and contents of Cyt C in mitochondria of brain tissues of 1,3,6,9,12 months old Kunming mice were detected using UV spectrophotometry. Results:CCO activity and contents of Cyt C in mitochondria of brain tissues were decreased gradually with the increase of mice age. Conclusion:CCO activity and contents of Cyt C in mitochondria of brain tissues may be used for age estimation.
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