引用本文:黄建伟,权正学.纳米羟基磷灰石/聚酰胺66颈椎融合器在颈前路椎间盘切除术后椎间隙重建的初期疗效[J].重庆医科大学学报,2013,(11):1271~1274
纳米羟基磷灰石/聚酰胺66颈椎融合器在颈前路椎间盘切除术后椎间隙重建的初期疗效
Initial curative effect of nano-hydroxyapattie/polyamide 66 cage in anterior cervical intervertebral disc discectomy and fusion
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中文关键词:  纳米羟基磷灰石/聚酰胺66  颈椎前路手术  椎间融合器
英文关键词:nano-hydroxyapatie/polyamide 66  anterior cervical surgery  interbody fusion cage
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黄建伟,权正学 重庆医科大学附属第一医院骨科重庆 400016 
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中文摘要:
      目的:观察纳米羟基磷灰石/聚酰胺66(nano-hydroxyapatie/polyamide 66,n-HA/PA66)颈椎融合器在颈前路椎间盘切除减压术后椎间隙植骨重建的初期疗效。方法:回顾性分析2008年6月-2011年6月行颈前路椎间盘切除减压,n-HA/PA66 颈椎融合器植骨融合,钛钉板系统固定治疗,资料完整的46例脊髓型和神经根型颈椎病及颈椎间盘突出症患者。影像学评价手术节段植骨融合率、塌陷率、椎间隙高度及颈椎曲度;Odom’s标准评定临床疗效。结果:Odom’s标准评定临床疗效,优良率80%。46例患者在术后6月时获得100%植骨融合率,未发现1例患者塌陷;椎间曲度由术前(2.29±3.04)°矫正到(8.04±3.06)°,术前较术后差异有统计学意义(P<0.05),末次随访时为(6.58±2.35)°,平均丢失角度为(1.45±1.96)°;术后6个月平均椎间隙高度(7.76±0.55) mm,较术前(4.40±1.36) mm差异有统计学意义(P<0.05),末次随访发现椎间隙高度(7.36±0.59) mm,丢失高度(0.41±0.28) mm。结论:n-HA/PA66颈椎融合器治疗颈前路椎间盘切除术后椎间隙重建具有良好的临床疗效,可有效的维持颈椎生理曲度和椎间隙高度,植骨融合率高。
英文摘要:
      Objective:To evaluate the preliminary efficacy of nano-hydroxyapatite/polyamide 66(n-HA/PA66) cage in reconstruction following anterior cervical intervertebral discectomy and fusion in cervical spondylosis. Methods:Clinical data of 46 patients with cer-vical spondylopathy and cervical disc herniation who underwent anterior cervical intervertebral discectomy and fusion between June 2008 and June 2011 were retrospectively analyzed. Cervical pathologies included cervial spondylotic myelopathy and cervical radicu-lopathy. All patients were assessed clinically and radiologically. Clinical outcome was evaluated using Odom’s criteria;radiology results included subsidence of the cages,angle of cervical lordosis,fusion rate and intervertebral height. Results:Based on Odom’s criteria,excellent rate was 80%. All cases achieved graft fusion at 6 months after the operation without displacement and subsidence. There were significant differences in angle of cervical lordosis between preoperation and 6 months after operation((2.29±3.04)° vs. (8.04±3.06)°,P<0.05);last follow-up showed(6.58±2.35)° and the mean loss of angle of cervical lordosis was (1.45±1.96)°. There were significant differences in intervertebral height between preoperation and at 6 months after the operation((7.76±0.55) mm vs. (4.40±1.36) mm,P<0.05);last follow-up showed(7.36±0.59) mm and the mean loss of intervertebral height was (0.41±0.28) mm. Conclusions:n-HA/PA66 cage is effectively in the reconstruction following anterior cervical intervertebral discectomy and fusion since it can effec-tively maintain the biological alignment and cervical intervertebral height with high fusion rate.
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